Effect of mouthwash containing dextranase enzyme on markers related to dental cariese

Abstract

This study investigated the effect of mouthwash containing Dextranase enzyme which affected to the changes of dental plaque (Plague Index) in eighteen dental caries volunteers by two mouthwash formulas; Formula I contained only Dextranase enzyme whereas Formula II contained a mixture of Nisin and Dextranase enzymes. This study was a single blind randomized clinical trial study. All participants were divided into two equal number of groups received mouthwash containing Dextranase enzyme or mouthwash containing a mixture of Nisin and Dextranase enzyme after using mouthwash. The study allowed participants to use mouthwash continuously for at least four weeks. The participants received oral examination, oral digital imaging and proximal radiographs using Bitewing oral Imaging method, respectively. Both before and after using mouthwash were found to have dental caries. The study found that plague index in participants were decreased. © 2019 IEEE.