Publication:
Ovulation block by Pueraria mirifica: A study of its endocrinological effect in female monkeys

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dc.contributor.authorTrisomboon H.
dc.contributor.authorMalaivijitnond S.
dc.contributor.authorWatanabe G.
dc.contributor.authorTaya K.
dc.date.accessioned2021-04-05T04:32:37Z
dc.date.available2021-04-05T04:32:37Z
dc.date.issued2005
dc.date.issuedBE2548
dc.description.abstractPueraria mirifica (PM), a Thai herb containing phytoestrogens, may act as estrogen and disturb reproduction. To investigate the effect of PM on the menstrual cycle length and related hormones, nine adult female monkeys (Macaca fascicularis) were separated into three groups. Each group (n = 3) was fed with 10, 100, and 1000 mg/d of PM for three menstrual cycles. The menstrual cycle length increased significantly in mon-keys treated with PM-10 and PM-100 and disappeared completely in monkeys treated with PM-1000. Serum follicle stimulating hormone, luteinizing hormone, estradiol, progesterone, and ir-inhibin were lower during the treatment period in a dose-dependent manner. Changes in menstrual cycle length and the hormonal levels recovered during the post-treatment period only in monkeys treated with PM-10 and PM-100. PM greatly influences menstrual cycles and may suppress ovulation by lowering serum levels of gonadotropins. © 2005 by Humana Press Inc. All rights of any nature whatsoever reserved.
dc.format.mimetypeapplication/pdf
dc.identifier.citationEndocrine. Vol 26, No.1 (2005), p.33-39
dc.identifier.issn1355008X
dc.identifier.other2-s2.0-23844558954
dc.identifier.urihttps://swu-dspace2.eval.plus/handle/123456789/6170
dc.rights.holderScopus
dc.subject.otherEstradiol
dc.subject.otherFollitropin
dc.subject.otherGonadotropin
dc.subject.otherInhibin
dc.subject.otherLuteinizing hormone
dc.subject.otherPhytoestrogen
dc.subject.otherProgesterone
dc.subject.otherEstradiol
dc.subject.otherFollitropin
dc.subject.otherInhibin
dc.subject.otherLuteinizing hormone
dc.subject.otherPhytoestrogen
dc.subject.otherProgesterone
dc.subject.otherAnimal experiment
dc.subject.otherArticle
dc.subject.otherDose response
dc.subject.otherEstradiol blood level
dc.subject.otherFeeding
dc.subject.otherFemale
dc.subject.otherFollitropin blood level
dc.subject.otherGonadotropin blood level
dc.subject.otherHerb
dc.subject.otherHormone blood level
dc.subject.otherHormone determination
dc.subject.otherLuteinizing hormone blood level
dc.subject.otherMacaca
dc.subject.otherMenstrual cycle
dc.subject.otherMonkey
dc.subject.otherNonhuman
dc.subject.otherOvulation inhibition
dc.subject.otherPeuraria mirifica
dc.subject.otherPriority journal
dc.subject.otherProgesterone blood level
dc.subject.otherThailand
dc.subject.otherAnimal
dc.subject.otherBlood
dc.subject.otherDrug effect
dc.subject.otherMenstrual cycle
dc.subject.otherPueraria
dc.subject.otherAnimals
dc.subject.otherEstradiol
dc.subject.otherFemale
dc.subject.otherFollicle Stimulating Hormone
dc.subject.otherInhibins
dc.subject.otherLuteinizing Hormone
dc.subject.otherMacaca fascicularis
dc.subject.otherMenstrual Cycle
dc.subject.otherOvulation Inhibition
dc.subject.otherPhytoestrogens
dc.subject.otherProgesterone
dc.subject.otherPueraria
dc.titleOvulation block by Pueraria mirifica: A study of its endocrinological effect in female monkeys
dc.typeArticle
dspace.entity.typePublication
swu.datasource.scopushttps://www.scopus.com/inward/record.uri?eid=2-s2.0-23844558954&partnerID=40&md5=f3e64118fd049acaf2790128179b757c

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