Publication:
Sox9 is upstream of microRNA-140 in cartilage

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dc.contributor.authorNakamura Y.
dc.contributor.authorHe X.
dc.contributor.authorKato H.
dc.contributor.authorWakitani S.
dc.contributor.authorKobayashi T.
dc.contributor.authorWatanabe S.
dc.contributor.authorIida A.
dc.contributor.authorTahara H.
dc.contributor.authorWarman M.L.
dc.contributor.authorWatanapokasin R.
dc.contributor.authorPostlethwait J.H.
dc.date.accessioned2021-04-05T03:34:39Z
dc.date.available2021-04-05T03:34:39Z
dc.date.issued2012
dc.date.issuedBE2555
dc.description.abstractMicroRNA-140 (miR-140) is specifically expressed in developing cartilage tissues. We have previously reported that miR-140 plays an important role during palatal cartilage development by modulating platelet-derived growth factor receptor alpha (pdgfra) in zebrafish. However, the regulatory mechanism of miR-140 in cartilage is still unknown. Using developing zebrafish, sox9a mutant (sox9a-/-) and sox9b mutant (sox9b-/-) zebrafish and SOX9 small interfering RNA in human chondrocytes, T/C-28 cells, we found that miR-140 is regulated by the cartilage master transcription regulator Sox9 in zebrafish and mammalian cells. © 2011 Springer Science+Business Media, LLC.
dc.format.mimetypeapplication/pdf
dc.identifier.citationApplied Biochemistry and Biotechnology. Vol 166, No.1 (2012), p.64-71
dc.identifier.doi10.1007/s12010-011-9404-y
dc.identifier.issn2732289
dc.identifier.other2-s2.0-84856260583
dc.identifier.urihttps://swu-dspace2.eval.plus/handle/123456789/7144
dc.rights.holderScopus
dc.subject.otherIn situ hybridization
dc.subject.otherMicroRNA-140 (miR-140)
dc.subject.otherRT-PCR
dc.subject.otherSiRNA
dc.subject.otherSox9
dc.subject.otherT/C-28
dc.subject.otherZebrafish
dc.subject.otherMammals
dc.subject.otherPolymerase chain reaction
dc.subject.otherRNA
dc.subject.otherTissue
dc.subject.otherCartilage
dc.subject.otherMicroRNA
dc.subject.otherMicroRNA 140
dc.subject.otherMutant protein
dc.subject.otherPlatelet derived growth factor alpha receptor
dc.subject.otherSmall interfering RNA
dc.subject.otherTranscription factor Sox9
dc.subject.otherUnclassified drug
dc.subject.otherAnimal experiment
dc.subject.otherArticle
dc.subject.otherCartilage
dc.subject.otherCartilage cell
dc.subject.otherControlled study
dc.subject.otherHuman
dc.subject.otherHuman cell
dc.subject.otherIn situ hybridization
dc.subject.otherNonhuman
dc.subject.otherProtein expression
dc.subject.otherReverse transcription polymerase chain reaction
dc.subject.otherTranscription regulation
dc.subject.otherZebra fish
dc.subject.otherAnimals
dc.subject.otherBinding Sites
dc.subject.otherCartilage
dc.subject.otherChondrocytes
dc.subject.otherChondrogenesis
dc.subject.otherEmbryonic Development
dc.subject.otherGene Expression Regulation, Developmental
dc.subject.otherHumans
dc.subject.otherIn Situ Hybridization
dc.subject.otherMicroRNAs
dc.subject.otherPhylogeny
dc.subject.otherProtein Binding
dc.subject.otherRNA, Small Interfering
dc.subject.otherSOX9 Transcription Factor
dc.subject.otherUbiquitin-Protein Ligases
dc.subject.otherZebrafish
dc.subject.otherDanio rerio
dc.subject.otherMammalia
dc.titleSox9 is upstream of microRNA-140 in cartilage
dc.typeArticle
dspace.entity.typePublication
swu.datasource.scopushttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84856260583&doi=10.1007%2fs12010-011-9404-y&partnerID=40&md5=b7c62c3c83efc0cb97c7912a0ba81b75

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