Treatment of Documented Liver Metastasis from Cervical Cancer with High Dose of Chemoradiation

Abstract

Background: Most patients with advanced-stage cervical cancer have been treated with palliative intent. The aim of this article is to report chemoradiotherapy treatment in a patient who had a very good result. Case: A 56-year-old woman underwent laparoscopic staging for cervical cancer that had resulted in multiple nodules at the liver. Histopathology revealed that this was metastatic squamous-cell carcinoma from the primary cervical cancer. High doses of chemoradiotherapy was completed in 6 cycles. Results: Despite the side effects of her chemotherapy and the high-dose pelvic radiotherapy, this patient was able to tolerate the treatment cycles. She had remained in complete remission for sixteen years. After that, she subsequently developed an infection caused by a spontaneous rupture of her bladder, which was associated with radiation cystitis. She then developed sepsis and died. Conclusions: This report shows that laparoscopic surgical staging was associated with significant upstaging. The use of high-dose of chemoradiotherapy could prolong a patient's disease-free survival. © 2019, Mary Ann Liebert, Inc., publishers.